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The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes
Vacuolar protein sorting 9 (VPS9)–ankyrin-repeat protein (Varp) has recently been identified as an effector molecule for two small GTPases—Rab32 and Rab38—in the transport of a melanogenic enzyme tyrosinase-related protein 1 (Tyrp1) to melanosomes in melanocytes. Although Varp contains a Rab21–guani...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3279394/ https://ncbi.nlm.nih.gov/pubmed/22171327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-04-0324 |
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