Lifeguard Inhibits Fas Ligand-mediated Endoplasmic Reticulum-Calcium Release Mandatory for Apoptosis in Type II Apoptotic Cells

Death receptors are members of the tumor necrosis factor receptor superfamily involved in the extrinsic apoptotic pathway. Lifeguard (LFG) is a death receptor antagonist mainly expressed in the nervous system that specifically blocks Fas ligand (FasL)-induced apoptosis. To investigate its mechanism...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Urresti, Jorge, Ruiz-Meana, Marisol, Coccia, Elena, Arévalo, Juan Carlos, Castellano, José, Fernández-Sanz, Celia, Galenkamp, Koen M. O., Planells-Ferrer, Laura, Moubarak, Rana S., Llecha-Cano, Núria, Reix, Stéphanie, García-Dorado, David, Barneda-Zahonero, Bruna, Comella, Joan X.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714210/
https://ncbi.nlm.nih.gov/pubmed/26582200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.677682
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