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Identification of QS-21 as an Inflammasome-activating Molecular Component of Saponin Adjuvants
Many immunostimulants act as vaccine adjuvants via activation of the innate immune system, although in many cases it is unclear which specific molecules contribute to the stimulatory activity. QS-21 is a defined, highly purified, and soluble saponin adjuvant currently used in licensed and explorator...
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| Publicado en: | J Biol Chem |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4714196/ https://ncbi.nlm.nih.gov/pubmed/26555265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.683011 |
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