Effects of Toll-like receptor antagonist 4,5-dihydro-3-phenyl-5-isoxasole acetic acid on the progression of kidney disease in mice on a high-fat diet

BACKGROUND: Obesity-related metabolic disorders are closely associated with inflammation induced by innate immunity. Toll-like receptors (TLRs) play a pivotal role in the innate immune system by activating proinflammatory signaling pathways. GIT27 (4,5-dihydro-3-phenyl-5-isoxasole acetic acid) is an...

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Udgivet i:Kidney Res Clin Pract
Main Authors: Min, Hye Sook, Kim, Jung Eun, Lee, Mi Hwa, Song, Hye Kyoung, Lee, Mi Jin, Lee, Ji Eun, Kim, Hyun Wook, Cha, Jin Joo, Hyun, Young Youl, Han, Jee Young, Cha, Dae Ryong, Kang, Young Sun
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714156/
https://ncbi.nlm.nih.gov/pubmed/26877948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.krcp.2013.11.002
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