Effects of Toll-like receptor antagonist 4,5-dihydro-3-phenyl-5-isoxasole acetic acid on the progression of kidney disease in mice on a high-fat diet

BACKGROUND: Obesity-related metabolic disorders are closely associated with inflammation induced by innate immunity. Toll-like receptors (TLRs) play a pivotal role in the innate immune system by activating proinflammatory signaling pathways. GIT27 (4,5-dihydro-3-phenyl-5-isoxasole acetic acid) is an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Kidney Res Clin Pract
Prif Awduron: Min, Hye Sook, Kim, Jung Eun, Lee, Mi Hwa, Song, Hye Kyoung, Lee, Mi Jin, Lee, Ji Eun, Kim, Hyun Wook, Cha, Jin Joo, Hyun, Young Youl, Han, Jee Young, Cha, Dae Ryong, Kang, Young Sun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2014
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714156/
https://ncbi.nlm.nih.gov/pubmed/26877948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.krcp.2013.11.002
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