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Suppression of hedgehog signaling regulates hepatic stellate cell activation and collagen secretion

Hepatic stellate cells (HSCs) play an important role in liver fibrosis. This study investigates the expression of hedgehog in HSC and the role of hedgehog signaling on activation and collagen secretion of HSC. Liver ex vivo perfusion with collagenase IV and density gradient centrifugation were used...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Li, Tao, Leng, Xi-Sheng, Zhu, Ji-Ye, Wang, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713566/
https://ncbi.nlm.nih.gov/pubmed/26823780
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