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Suppression of hedgehog signaling regulates hepatic stellate cell activation and collagen secretion

Hepatic stellate cells (HSCs) play an important role in liver fibrosis. This study investigates the expression of hedgehog in HSC and the role of hedgehog signaling on activation and collagen secretion of HSC. Liver ex vivo perfusion with collagenase IV and density gradient centrifugation were used...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Clin Exp Pathol
Hauptverfasser: Li, Tao, Leng, Xi-Sheng, Zhu, Ji-Ye, Wang, Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713566/
https://ncbi.nlm.nih.gov/pubmed/26823780
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