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Endocytosis of collagen by hepatic stellate cells regulates extracellular matrix dynamics
Hepatic stellate cells (HSCs) generate matrix, which in turn may also regulate HSCs function during liver fibrosis. We hypothesized that HSCs may endocytose matrix proteins to sense and respond to changes in microenvironment. Primary human HSCs, LX2, or mouse embryonic fibroblasts (MEFs) [wild-type;...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4187054/ https://ncbi.nlm.nih.gov/pubmed/25080486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00086.2014 |
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