Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling

The molecular mechanisms of thymosin beta-4 (TB4) involved in regulating hepatic stellate cell (HSC) functions remain unclear. Therefore, we hypothesize that TB4 influences HSC activation through hedgehog (Hh) pathway. HSC functions declined in a TB4 siRNA-treated LX-2. TB4 suppression down-regulate...

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發表在:Sci Rep
Main Authors: Kim, Jieun, Hyun, Jeongeun, Wang, Sihyung, Lee, Chanbin, Lee, Jae-Wook, Moon, Eun-Yi, Cha, Heejae, Diehl, Anna Mae, Jung, Youngmi
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476572/
https://ncbi.nlm.nih.gov/pubmed/28630423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03782-x
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