Clinicopathological risk factor distributions for MLH1 promoter region methylation in CIMP positive tumors

BACKGROUND: The CpG Island Methylator Phenotype (CIMP) is a major molecular pathway in colorectal cancer (CRC). Approximately 25% to 60% of CIMP tumors are microsatellite unstable (MSI-H) due to DNA hypermethylation of the MLH1 gene promoter. Our aim was to determine if the distributions of clinicop...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cancer Epidemiol Biomarkers Prev
Hlavní autoři: Levine, A. Joan, Phipps, Amanda I., Baron, John A., Buchanan, Daniel D., Ahnen, Dennis J., Cohen, Stacey A., Lindor, Noralane M., Newcomb, Polly A., Rosty, Christophe, Haile, Robert W., Laird, Peter W., Weisenberger, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713308/
https://ncbi.nlm.nih.gov/pubmed/26512054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-15-0935
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky