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Discovery of a new method for potent drug development using power function of stoichiometry ofhomomeric biocomplexes or biological nanomotors

INTRODUCTION: Multidrug resistance and the appearance of incurable diseases inspire the quest for potent therapeutics. AREAS COVERED: We review a new methodology in designing potent drugs by targeting multi-subunit homomeric biological motors, machines, or complexes with Z>1 and K=1, where Z is t...

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Detalhes bibliográficos
Publicado no:Expert Opin Drug Deliv
Main Authors: Pi, Fengmei, Vieweger, Mario, Zhao, Zhengyi, Wang, Shaoying, Guo, Peixuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713257/
https://ncbi.nlm.nih.gov/pubmed/26307193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425247.2015.1082544
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