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Development of Potent Antiviral Drugs Inspired by Viral Hexameric DNA-Packaging Motors with Revolving Mechanism

The intracellular parasitic nature of viruses and the emergence of antiviral drug resistance necessitate the development of new potent antiviral drugs. Recently, a method for developing potent inhibitory drugs by targeting biological machines with high stoichiometry and a sequential-action mechanism...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Pi, Fengmei, Zhao, Zhengyi, Chelikani, Venkata, Yoder, Kristine, Kvaratskhelia, Mamuka, Guo, Peixuan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008075/
https://ncbi.nlm.nih.gov/pubmed/27356896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00508-16
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