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Protective Effect of Creatine Elevation against Ischaemia Reperfusion Injury Is Retained in the Presence of Co-Morbidities and during Cardioplegia

AIMS: Ischaemic heart disease is most prevalent in the ageing population and often exists with other comorbidities; however the majority of laboratory research uses young, healthy animal models. Several recent workshops and focus meetings have highlighted the importance of using clinically relevant...

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Publicado en:PLoS One
Autores principales: Whittington, Hannah J., McAndrew, Debra J., Cross, Rebecca L., Neubauer, Stefan, Lygate, Craig A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713158/
https://ncbi.nlm.nih.gov/pubmed/26765737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146429
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