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PAF Complex Plays Novel Subunit-Specific Roles in Alternative Cleavage and Polyadenylation

The PAF complex (Paf1C) has been shown to regulate chromatin modifications, gene transcription, and RNA polymerase II (PolII) elongation. Here, we provide the first genome-wide profiles for the distribution of the entire complex in mammalian cells using chromatin immunoprecipitation and high through...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Yang, Yan, Li, Wencheng, Hoque, Mainul, Hou, Liming, Shen, Steven, Tian, Bin, Dynlacht, Brian D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713055/
https://ncbi.nlm.nih.gov/pubmed/26765774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005794
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