Neuregulin-1-mediated ErbB2–ErbB3 signalling protects human trophoblasts against apoptosis to preserve differentiation

During placentation, foetal trophoblasts invade deeply into maternal tissue to establish a foeto–maternal circulation. We have previously shown that extravillous trophoblast (EVT) lineage cells express ErbB2 and ErbB3, of which the potential as an oncogenic unit is well established. However, a physi...

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Bibliografiska uppgifter
I publikationen:J Cell Sci
Huvudupphovsmän: Fock, Valerie, Plessl, Kerstin, Draxler, Peter, Otti, Gerlinde Regina, Fiala, Christian, Knöfler, Martin, Pollheimer, Jürgen
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712818/
https://ncbi.nlm.nih.gov/pubmed/26490994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.176933
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