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The role of neuregulin/ErbB2/ErbB4 signaling in the heart with special focus on effects on cardiomyocyte proliferation

The signaling complex consisting of the growth factor neuregulin-1 (NRG1) and its tyrosine kinase receptors ErbB2 and ErbB4 has a critical role in cardiac development and homeostasis of the structure and function of the adult heart. Recent research results suggest that targeting this signaling compl...

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Détails bibliographiques
Auteurs principaux: Wadugu, Brian, Kühn, Bernhard
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378290/
https://ncbi.nlm.nih.gov/pubmed/22427524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00063.2012
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