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Activation of m1 muscarinic acetylcholine receptor induces surface transport of KCNQ channels through a CRMP-2-mediated pathway

Neuronal excitability is strictly regulated by various mechanisms, including modulation of ion channel activity and trafficking. Stimulation of m1 muscarinic acetylcholine receptor (also known as CHRM1) increases neuronal excitability by suppressing the M-current generated by the Kv7/KCNQ channel fa...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Jiang, Ling, Kosenko, Anastasia, Yu, Clinton, Huang, Lan, Li, Xuejun, Hoshi, Naoto
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712786/
https://ncbi.nlm.nih.gov/pubmed/26446259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.175547
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