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Reduced levels of protein recoding by A-to-I RNA editing in Alzheimer's disease
Adenosine to inosine (A-to-I) RNA editing, catalyzed by the ADAR enzyme family, acts on dsRNA structures within pre-mRNA molecules. Editing of the coding part of the mRNA may lead to recoding, amino acid substitution in the resulting protein, possibly modifying its biochemical and biophysical proper...
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| Udgivet i: | RNA |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4712678/ https://ncbi.nlm.nih.gov/pubmed/26655226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.054627.115 |
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