Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in Zebrafish

Fragile X syndrome (FXS) is the most frequent inherited form of mental retardation. The cause for this X-linked disorder is the silencing of the fragile X mental retardation 1 (fmr1) gene and the absence of the fragile X mental retardation protein (Fmrp). The RNA-binding protein Fmrp represses prote...

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Vydáno v:PLoS Genet
Hlavní autoři: Shamay-Ramot, Adi, Khermesh, Khen, Porath, Hagit T., Barak, Michal, Pinto, Yishay, Wachtel, Chaim, Zilberberg, Alona, Lerer-Goldshtein, Tali, Efroni, Sol, Levanon, Erez Y., Appelbaum, Lior
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670233/
https://ncbi.nlm.nih.gov/pubmed/26637167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005702
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