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Conformational dynamics of stem II of the U2 snRNA

The spliceosome undergoes dramatic changes in both small nuclear RNA (snRNA) composition and structure during assembly and pre-mRNA splicing. It has been previously proposed that the U2 snRNA adopts two conformations within the stem II region: stem IIa or stem IIc. Dynamic rearrangement of stem IIa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:RNA
Hauptverfasser: Rodgers, Margaret L., Tretbar, U. Sandy, Dehaven, Alexander, Alwan, Amir A., Luo, George, Mast, Hannah M., Hoskins, Aaron A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712673/
https://ncbi.nlm.nih.gov/pubmed/26631165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.052233.115
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