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Effects of Cytochrome P450 Inhibition and Induction on the Phenotyping Metrics of the Basel Cocktail: A Randomized Crossover Study
BACKGROUND AND OBJECTIVE: Activity of human cytochrome P450 enzymes (CYPs) shows high inter-and intra-individual variability, which is determined by genetic and non-genetic factors. Using a combination of CYP-specific probe drugs, phenotyping cocktails allow simultaneous assessment of the activity o...
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| Publicado en: | Clin Pharmacokinet |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer International Publishing
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4712254/ https://ncbi.nlm.nih.gov/pubmed/26123704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-015-0294-y |
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