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Strong Expression of Hypoxia-Inducible Factor-1α (HIF-1α) Is Associated with Axl Expression and Features of Aggressive Tumors in African Breast Cancer

PURPOSE: Inhibition of hypoxia-inducible factor (HIF) and Axl receptor tyrosine kinase is being evaluated for targeted therapy in solid tumors. Both HIF-1α and Axl influence tumor growth and metastatic potential, and they have been linked to treatment failure in many cancers. However, there is a lac...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Nalwoga, Hawa, Ahmed, Lavina, Arnes, Jarle B., Wabinga, Henry, Akslen, Lars A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711940/
https://ncbi.nlm.nih.gov/pubmed/26760782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146823
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