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Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer

We here examined whether Nestin, by protein and mRNA levels, could be a predictor of BRCA1 related breast cancer, a basal-like phenotype, and aggressive tumours. Immunohistochemical staining of Nestin was done in independent breast cancer hospital cohorts (Series I-V, total 1257 cases). Also, TCGA p...

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發表在:Sci Rep
Main Authors: Krüger, Kristi, Wik, Elisabeth, Knutsvik, Gøril, Nalwoga, Hawa, Klingen, Tor A., Arnes, Jarle B., Chen, Ying, Mannelqvist, Monica, Dimitrakopoulou, Konstantina, Stefansson, Ingunn M., Birkeland, Even, Aas, Turid, Tobin, Nicholas P., Jonassen, Inge, Bergh, Jonas, Foulkes, William D., Akslen, Lars A.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430803/
https://ncbi.nlm.nih.gov/pubmed/28439082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00862-w
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