Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer

We here examined whether Nestin, by protein and mRNA levels, could be a predictor of BRCA1 related breast cancer, a basal-like phenotype, and aggressive tumours. Immunohistochemical staining of Nestin was done in independent breast cancer hospital cohorts (Series I-V, total 1257 cases). Also, TCGA p...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Krüger, Kristi, Wik, Elisabeth, Knutsvik, Gøril, Nalwoga, Hawa, Klingen, Tor A., Arnes, Jarle B., Chen, Ying, Mannelqvist, Monica, Dimitrakopoulou, Konstantina, Stefansson, Ingunn M., Birkeland, Even, Aas, Turid, Tobin, Nicholas P., Jonassen, Inge, Bergh, Jonas, Foulkes, William D., Akslen, Lars A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430803/
https://ncbi.nlm.nih.gov/pubmed/28439082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00862-w
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