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Harnessing Hidden Anti-Tumor Power of MLL-AF4 Oncogene to Fight Leukemia

It is unclear whether the anti-proliferative/pro-apoptotic activity of oncogenes can be pharmacologically reactivated in cancer cells. In this issue of Cancer Cell, Liu and colleagues report that a proteasome inhibitor reactivates an MLL-AF4 controlled anti-tumor program to kill leukemia cells in an...

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Foilsithe in:Cancer Cell
Main Authors: Matkar, Smita, Katona, Bryson W., Hua, Xianxin
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711792/
https://ncbi.nlm.nih.gov/pubmed/24735921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.03.028
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