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Harnessing Hidden Anti-Tumor Power of MLL-AF4 Oncogene to Fight Leukemia
It is unclear whether the anti-proliferative/pro-apoptotic activity of oncogenes can be pharmacologically reactivated in cancer cells. In this issue of Cancer Cell, Liu and colleagues report that a proteasome inhibitor reactivates an MLL-AF4 controlled anti-tumor program to kill leukemia cells in an...
Shranjeno v:
| izdano v: | Cancer Cell |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4711792/ https://ncbi.nlm.nih.gov/pubmed/24735921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.03.028 |
| Oznake: |
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