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Statistical Evaluation of HTS Assays for Enzymatic Hydrolysis of β-Keto Esters

β-keto esters are used as precursors for the synthesis of β-amino acids, which are building blocks for some classes of pharmaceuticals. Here we describe the comparison of screening procedures for hydrolases to be used for the hydrolysis of β-keto esters, the first step in the preparation of β-amino...

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發表在:PLoS One
Main Authors: Buß, O., Jager, S., Dold, S. -M., Zimmermann, S., Hamacher, K., Schmitz, K., Rudat, J.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711668/
https://ncbi.nlm.nih.gov/pubmed/26730596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146104
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