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β-Phenylalanine Ester Synthesis from Stable β-Keto Ester Substrate Using Engineered ω-Transaminases

The successful synthesis of chiral amines from ketones using ω-transaminases has been shown in many cases in the last two decades. In contrast, the amination of β-keto acids is a special and relatively new challenge, as they decompose easily in aqueous solution. To avoid this, transamination of the...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Buß, Oliver, Voss, Moritz, Delavault, André, Gorenflo, Pascal, Syldatk, Christoph, Bornscheuer, Uwe, Rudat, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100204/
https://ncbi.nlm.nih.gov/pubmed/29783679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23051211
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