Serial femtosecond X-ray diffraction of enveloped virus microcrystals

Serial femtosecond crystallography (SFX) using X-ray free-electron lasers has produced high-resolution, room temperature, time-resolved protein structures. We report preliminary SFX of Sindbis virus, an enveloped icosahedral RNA virus with ∼700 Å diameter. Microcrystals delivered in viscous agarose...

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Dades bibliogràfiques
Publicat a:Struct Dyn
Autors principals: Lawrence, Robert M., Conrad, Chelsie E., Zatsepin, Nadia A., Grant, Thomas D., Liu, Haiguang, James, Daniel, Nelson, Garrett, Subramanian, Ganesh, Aquila, Andrew, Hunter, Mark S., Liang, Mengning, Boutet, Sébastien, Coe, Jesse, Spence, John C. H., Weierstall, Uwe, Liu, Wei, Fromme, Petra, Cherezov, Vadim, Hogue, Brenda G.
Format: Artigo
Idioma:Inglês
Publicat: American Crystallographic Association 2015
Matèries:
SPECIAL TOPIC: BIOLOGY WITH X-RAY LASERS 2
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711640/
https://ncbi.nlm.nih.gov/pubmed/26798819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4929410
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