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Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography

Membrane proteins (MPs) are essential components of cellular membranes and primary drug targets. Rational drug design relies on precise structural information, typically obtained by crystallography; however MPs are difficult to crystallize. Recent progress in MP structural determination has benefite...

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Detaylı Bibliyografya
Yayımlandı:J Vis Exp
Asıl Yazarlar: Ishchenko, Andrii, Cherezov, Vadim, Liu, Wei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MyJove Corporation 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5092055/
https://ncbi.nlm.nih.gov/pubmed/27683972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54463
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