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Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography

Membrane proteins (MPs) are essential components of cellular membranes and primary drug targets. Rational drug design relies on precise structural information, typically obtained by crystallography; however MPs are difficult to crystallize. Recent progress in MP structural determination has benefite...

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Bibliografski detalji
Izdano u:J Vis Exp
Glavni autori: Ishchenko, Andrii, Cherezov, Vadim, Liu, Wei
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5092055/
https://ncbi.nlm.nih.gov/pubmed/27683972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54463
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