Serial femtosecond X-ray diffraction of enveloped virus microcrystals

Serial femtosecond crystallography (SFX) using X-ray free-electron lasers has produced high-resolution, room temperature, time-resolved protein structures. We report preliminary SFX of Sindbis virus, an enveloped icosahedral RNA virus with ∼700 Å diameter. Microcrystals delivered in viscous agarose...

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Bibliografske podrobnosti
izdano v:Struct Dyn
Main Authors: Lawrence, Robert M., Conrad, Chelsie E., Zatsepin, Nadia A., Grant, Thomas D., Liu, Haiguang, James, Daniel, Nelson, Garrett, Subramanian, Ganesh, Aquila, Andrew, Hunter, Mark S., Liang, Mengning, Boutet, Sébastien, Coe, Jesse, Spence, John C. H., Weierstall, Uwe, Liu, Wei, Fromme, Petra, Cherezov, Vadim, Hogue, Brenda G.
Format: Artigo
Jezik:Inglês
Izdano: American Crystallographic Association 2015
Teme:
SPECIAL TOPIC: BIOLOGY WITH X-RAY LASERS 2
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711640/
https://ncbi.nlm.nih.gov/pubmed/26798819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4929410
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