N-acetylcysteine renoprotection in methotrexate induced nephrotoxicity and its effects on B-cell lymphoma

BACKGROUND: Nephrotoxicity is one of the known side effects of methotrexate (MTX) therapy despite the use of conventional protective measures. Our objectives were to evaluate the effects of N-acetylcysteine (NAC) on MTX-induced toxicity in renal tubular cells and to evaluate whether adjunctive use o...

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Bibliographic Details
Published in:Indian J Med Paediatr Oncol
Main Authors: Singh, Ruchi, Shah, Rikin, Turner, Curtis, Regueira, Osvaldo, Vasylyeva, Tetyana L.
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711223/
https://ncbi.nlm.nih.gov/pubmed/26811594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-5851.171545
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