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Rational Redesign of the 4-Chlorobenzoate Binding Site of 4-Chlorobenzoate: Coenzyme A Ligase for Expanded Substrate Range()

Environmental aromatic acids are transformed to chemical energy in bacteria that possess the requisite secondary pathways. Some of these pathways rely on the activation of the aromatic acid by coenzyme A (CoA) thioesterification catalyzed by an aromatic acid: CoA ligase. Adaptation of such pathways...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Wu, Rui, Reger, Albert S., Cao, Jian, Gulick, Andrew M., Dunaway-Mariano, Debra
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710512/
https://ncbi.nlm.nih.gov/pubmed/18027984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi701609w
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