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L-Dopa induced dyskinesias in Parkinsonian mice: disease severity or L-Dopa history
In Parkinson's disease, the efficacy of L-Dopa treatment changes over time, as dyskinesias emerge with previously beneficial doses. Using MitoPark mice, that models mitochondrial failure in dopamine (DA) neurons and mimics the progressive loss of dopamine observed in Parkinson’s disease, we fou...
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| Publicado no: | Brain Res |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4710145/ https://ncbi.nlm.nih.gov/pubmed/26086365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2015.06.005 |
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