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The complexity of protein energy landscapes studied by solution NMR relaxation dispersion experiments

The millisecond timescale motions in ribonuclease A (RNase A) were studied by solution NMR CPMG and off-resonance R(1ρ) relaxation dispersion experiments over a wide pH and temperature range. These experiments identify three separate protein regions termed Cluster 1, Cluster 2, and R33 whose motions...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Khirich, Gennady, Loria, J. Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710144/
https://ncbi.nlm.nih.gov/pubmed/25680027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.5b00212
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