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Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis

Alterations in oxidative phosphorylation resulting from mitochondrial dysfunction have long been hypothesized to be involved in tumorigenesis. Mitochondria have recently been shown to play an important role in regulating both programmed cell death and cell proliferation. Furthermore, mitochondrial D...

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Dettagli Bibliografici
Pubblicato in:Cell Res
Autori principali: Lu, Jianxin, Sharma, Lokendra Kumar, Bai, Yidong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710094/
https://ncbi.nlm.nih.gov/pubmed/19532122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2009.69
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