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Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis

Alterations in oxidative phosphorylation resulting from mitochondrial dysfunction have long been hypothesized to be involved in tumorigenesis. Mitochondria have recently been shown to play an important role in regulating both programmed cell death and cell proliferation. Furthermore, mitochondrial D...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Lu, Jianxin, Sharma, Lokendra Kumar, Bai, Yidong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710094/
https://ncbi.nlm.nih.gov/pubmed/19532122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2009.69
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