Low expression of estrogen receptor β in T lymphocytes and high serum levels of anti-estrogen receptor α antibodies impact disease activity in female patients with systemic lupus erythematosus

BACKGROUND: Current evidence indicates that estrogens, in particular 17β-estradiol (E2), play a crucial role in the gender bias of autoimmune diseases although the underlying molecular mechanisms have not yet been fully elucidated. Immune cells have estrogen receptors (ERs), i.e., ERα and ERβ, that...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Biol Sex Differ
Autores principales: Maselli, Angela, Conti, Fabrizio, Alessandri, Cristiano, Colasanti, Tania, Barbati, Cristiana, Vomero, Marta, Ciarlo, Laura, Patrizio, Mario, Spinelli, Francesca Romana, Ortona, Elena, Valesini, Guido, Pierdominici, Marina
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709986/
https://ncbi.nlm.nih.gov/pubmed/26759713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-016-0057-y
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares