T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy

Autophagy, the cytoprotection mechanism that takes place under metabolic impairment, has been implicated in the pathogenesis of autoimmunity. Here, we investigated the spontaneous and induced autophagic behavior of T lymphocytes from patients with systemic lupus erythematosus (SLE) compared with tha...

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Bibliographic Details
Main Authors: Alessandri, Cristiano, Barbati, Cristiana, Vacirca, Davide, Piscopo, Paola, Confaloni, Annamaria, Sanchez, Massimo, Maselli, Angela, Colasanti, Tania, Conti, Fabrizio, Truglia, Simona, Perl, Andras, Valesini, Guido, Malorni, Walter, Ortona, Elena, Pierdominici, Marina
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2012
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475261/
https://ncbi.nlm.nih.gov/pubmed/22835828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-206060
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