T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy

Autophagy, the cytoprotection mechanism that takes place under metabolic impairment, has been implicated in the pathogenesis of autoimmunity. Here, we investigated the spontaneous and induced autophagic behavior of T lymphocytes from patients with systemic lupus erythematosus (SLE) compared with tha...

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Detalhes bibliográficos
Main Authors: Alessandri, Cristiano, Barbati, Cristiana, Vacirca, Davide, Piscopo, Paola, Confaloni, Annamaria, Sanchez, Massimo, Maselli, Angela, Colasanti, Tania, Conti, Fabrizio, Truglia, Simona, Perl, Andras, Valesini, Guido, Malorni, Walter, Ortona, Elena, Pierdominici, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2012
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475261/
https://ncbi.nlm.nih.gov/pubmed/22835828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-206060
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