Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease

BACKGROUND: The discovery that heterozygous missense mutations in the gene encoding triggering receptor expressed on myeloid cells 2 (TREM2) are risk factors for Alzheimer’s disease (AD), with only the apolipoprotein E (APOE) ε4 gene allele conferring a higher risk, has led to increased interest in...

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Détails bibliographiques
Publié dans:Mol Neurodegener
Auteurs principaux: Heslegrave, Amanda, Heywood, Wendy, Paterson, Ross, Magdalinou, Nadia, Svensson, Johan, Johansson, Per, Öhrfelt, Annika, Blennow, Kaj, Hardy, John, Schott, Jonathan, Mills, Kevin, Zetterberg, Henrik
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Short Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709982/
https://ncbi.nlm.nih.gov/pubmed/26754172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0071-x
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