High-Throughput Screen in Cryptococcus neoformans Identifies a Novel Molecular Scaffold That Inhibits Cell Wall Integrity Pathway Signaling

[Image: see text] Cryptococcus neoformans is one of the most important human fungal pathogens; however, no new therapies have been developed in over 50 years. Fungicidal activity is crucially important for an effective anticryptococal agent and, therefore, we screened 361,675 molecules against C. ne...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:ACS Infect Dis
मुख्य लेखकों: Hartland, Kate, Pu, Jun, Palmer, Michelle, Dandapani, Sivaraman, Moquist, Philip N., Munoz, Benito, DiDone, Louis, Schreiber, Stuart L., Krysan, Damian J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Chemical Society 2015
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709821/
https://ncbi.nlm.nih.gov/pubmed/26807437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.5b00111
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