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High-Throughput Screen in Cryptococcus neoformans Identifies a Novel Molecular Scaffold That Inhibits Cell Wall Integrity Pathway Signaling
[Image: see text] Cryptococcus neoformans is one of the most important human fungal pathogens; however, no new therapies have been developed in over 50 years. Fungicidal activity is crucially important for an effective anticryptococal agent and, therefore, we screened 361,675 molecules against C. ne...
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Publicado no: | ACS Infect Dis |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Chemical
Society
2015
|
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4709821/ https://ncbi.nlm.nih.gov/pubmed/26807437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.5b00111 |
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