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Contact-facilitated drug delivery with Sn2 lipase labile prodrugs optimize targeted lipid nanoparticle drug delivery

Sn2 lipase labile phospholipid prodrugs in conjunction with contact-facilitated drug delivery offer an important advancement in Nanomedicine. Many drugs incorporated into nanosystems, targeted or not, are substantially lost during circulation to the target. However, favorably altering the pharmacoki...

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Détails bibliographiques
Publié dans:Wiley Interdiscip Rev Nanomed Nanobiotechnol
Auteurs principaux: Pan, Dipanjan, Pham, Christine TN, Weilbaecher, Katherine N, Tomasson, Michael H, Wickline, Samuel A, Lanza, Gregory M
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709477/
https://ncbi.nlm.nih.gov/pubmed/26296541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wnan.1355
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