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Mevalonate Pathway Regulates Cell Size Homeostasis and Proteostasis through Autophagy

Balance between cell growth and proliferation determines cell size homeostasis, but little is known about how metabolic pathways are involved in the maintenance of this balance. Here, we perform a screen with a library of clinically used drug molecules for their effects on cell size. We find that st...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Miettinen, Teemu P., Björklund, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709259/
https://ncbi.nlm.nih.gov/pubmed/26686643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.11.045
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