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Mevalonate Pathway Regulates Cell Size Homeostasis and Proteostasis through Autophagy

Balance between cell growth and proliferation determines cell size homeostasis, but little is known about how metabolic pathways are involved in the maintenance of this balance. Here, we perform a screen with a library of clinically used drug molecules for their effects on cell size. We find that st...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Rep
Prif Awduron: Miettinen, Teemu P., Björklund, Mikael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cell Press 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709259/
https://ncbi.nlm.nih.gov/pubmed/26686643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.11.045
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