Lysosomal homeostasis regulates myocardial ischemia-reperfusion injury through autophagy pathway

Abstract This study aims to elucidate the dual role of lysosomal homeostasis in regulating autophagic flux during myocardial ischemia/reperfusion injury (MIRI). Using a rat MIRI model and primary myocardial cell hypoxia/reoxygenation (HR) model, we assessed the changes in autophagic flux through the...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Yi Li, Yanfang Liu, Hui Wu, Songlin Zhang, Di Liu, Xiaoli Huang, Gang Zhou, Dong Zhang, Xiaoting Yang, Tian Zhou, Yan Xiong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-10-01
coleção:	Scientific Reports
Assuntos:	Ischemia-reperfusion injury Autophagy Lysosome homeostasis Autosis
Acesso em linha:	https://doi.org/10.1038/s41598-025-20853-6
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!