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Epigenetic regulation of UBE3A and roles in human neurodevelopmental disorders

The E3 ubiquitin ligase UBE3A, also known as E6-AP, has a multitude of ascribed functions and targets relevant to human health and disease. Epigenetic regulation of the UBE3A gene by parentally imprinted noncoding transcription within human chromosome 15q11.2–q13.3 is responsible for the maternal-sp...

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Détails bibliographiques
Publié dans:Epigenomics
Auteurs principaux: LaSalle, Janine M, Reiter, Lawrence T, Chamberlain, Stormy J
Format: Artigo
Langue:Inglês
Publié: Future Medicine Ltd 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709177/
https://ncbi.nlm.nih.gov/pubmed/26585570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.15.70
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