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Irradiation-injured brain tissues can self-renew in the absence of the pivotal tumor suppressor p53 in the medaka ( Oryzias latipes ) embryo
The tumor suppressor protein, p53, plays pivotal roles in regulating apoptosis and proliferation in the embryonic and adult central nervous system (CNS) following neuronal injuries such as those induced by ionizing radiation. There is increasing evidence that p53 negatively regulates the self-renewa...
Enregistré dans:
| Publié dans: | J Radiat Res |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4708913/ https://ncbi.nlm.nih.gov/pubmed/26410759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrv054 |
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