Irradiation-injured brain tissues can self-renew in the absence of the pivotal tumor suppressor p53 in the medaka ( Oryzias latipes ) embryo

The tumor suppressor protein, p53, plays pivotal roles in regulating apoptosis and proliferation in the embryonic and adult central nervous system (CNS) following neuronal injuries such as those induced by ionizing radiation. There is increasing evidence that p53 negatively regulates the self-renewa...

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Bibliographische Detailangaben
Veröffentlicht in:J Radiat Res
Hauptverfasser: Yasuda, Takako, Kimori, Yoshitaka, Nagata, Kento, Igarashi, Kento, Watanabe-Asaka, Tomomi, Oda, Shoji, Mitani, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4708913/
https://ncbi.nlm.nih.gov/pubmed/26410759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrv054
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