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Irradiation-injured brain tissues can self-renew in the absence of the pivotal tumor suppressor p53 in the medaka ( Oryzias latipes ) embryo

The tumor suppressor protein, p53, plays pivotal roles in regulating apoptosis and proliferation in the embryonic and adult central nervous system (CNS) following neuronal injuries such as those induced by ionizing radiation. There is increasing evidence that p53 negatively regulates the self-renewa...

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Detalhes bibliográficos
Publicado no:J Radiat Res
Main Authors: Yasuda, Takako, Kimori, Yoshitaka, Nagata, Kento, Igarashi, Kento, Watanabe-Asaka, Tomomi, Oda, Shoji, Mitani, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4708913/
https://ncbi.nlm.nih.gov/pubmed/26410759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrv054
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