AB228. Tetrandrine blocks autophagic flux and induces apoptosis via energetic impairment in cancer cells

Lysosomes are acidic organelles that have a crucial role in degrading intracellular macromolecules and organelles during the final stage of autophagy. Tetrandrine (Tet), a bisbenzylisoquinoline alkaloid, was reported as an autophagy activator. Here, in contrast with previous studies, we show that Te...

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Publicado en:Transl Androl Urol
Main Authors: Qiu, Wei, Guan, Ruili, He, Wei, Gong, Yanqing, Guo, Yinglu
Formato: Artigo
Idioma:Inglês
Publicado: AME Publishing Company 2014
Assuntos:
Abstract Publication Basic Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4708505/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2223-4683.2014.s228
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