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Oral selective estrogen receptor downregulators (SERDs) a breakthrough endocrine therapy for breast cancer

Drugs that inhibit estrogen receptor alpha (ERα) or which block the production of estrogens remain frontline interventions in the treatment and management of breast cancer at all stages. However, resistance to endocrine therapies, especially in the setting of advanced disease, remains an impediment...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: McDonnell, Donald P., Wardell, Suzanne E., Norris, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4708081/
https://ncbi.nlm.nih.gov/pubmed/26039356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b00760
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