The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis

Master transcription factors interact with DNA to establish cell-type identity and to regulate gene expression in mammalian cells(1,2). The genome-wide map of these transcription factor binding sites has been termed the cistrome(3). Here we show that the androgen receptor (AR) cistrome undergoes ext...

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Veröffentlicht in:Nat Genet
Hauptverfasser: Pomerantz, Mark M., Li, Fugen, Takeda, David, Lenci, Romina, Chonkar, Apurva, Chabot, Matthew, Cejas, Paloma, Vazquez, Francisca, Cook, Jennifer, Shivdasani, Ramesh A., Bowden, Michaela, Lis, Rosina, Hahn, William C., Kantoff, Philip W., Brown, Myles, Loda, Massimo, Long, Henry W., Freedman, Matthew L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707683/
https://ncbi.nlm.nih.gov/pubmed/26457646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3419
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