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Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer

Lineage plasticity, the ability of a cell to alter its identity, is an increasingly common mechanism of adaptive resistance to targeted therapy in cancer. An archetypal example is the development of neuroendocrine prostate cancer (NEPC) after treatment of prostate adenocarcinoma (PRAD) with inhibito...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Baca, Sylvan C., Takeda, David Y., Seo, Ji-Heui, Hwang, Justin, Ku, Sheng Yu, Arafeh, Rand, Arnoff, Taylor, Agarwal, Supreet, Bell, Connor, O’Connor, Edward, Qiu, Xintao, Alaiwi, Sarah Abou, Corona, Rosario I., Fonseca, Marcos A. S., Giambartolomei, Claudia, Cejas, Paloma, Lim, Klothilda, He, Monica, Sheahan, Anjali, Nassar, Amin, Berchuck, Jacob E., Brown, Lisha, Nguyen, Holly M., Coleman, Ilsa M., Kaipainen, Arja, De Sarkar, Navonil, Nelson, Peter S., Morrissey, Colm, Korthauer, Keegan, Pomerantz, Mark M., Ellis, Leigh, Pasaniuc, Bogdan, Lawrenson, Kate, Kelly, Kathleen, Zoubeidi, Amina, Hahn, William C., Beltran, Himisha, Long, Henry W., Brown, Myles, Corey, Eva, Freedman, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010057/
https://ncbi.nlm.nih.gov/pubmed/33785741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22139-7
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